YAMAMOTO RESEARCH
Lipoxan New Formula 40 capsules

From the constant research of Yamamoto Research's R&D team comes Lipoxan New Formula, a food supplement developed to increase thermogenesis, stimulate metabolism and support slimming paths. Lipoxan New Formula is in fact a functional ally to be used during low-calorie diets aimed at reducing body weight or as a support to physical activity. Thanks to its natural formula, rich in raw materials with proven effects, Lipoxan New Formula can support and stimulate the metabolism and participate in maintaining body weight balance. Its exclusive composition boasts the synergy action of synephrine obtained from bitter orange extract, green coffee (45% chlorogenic acids and 5% caffeine), green tea, rich in polyphenols and EGCG, anhydrous caffeine,

The extracts of green tea, green coffee and chilli have been specially selected for their contribution to body weight balance (green tea), for their tonic and metabolic support action (green coffee) and for their metabolism stimulation (chilli ). These 3 extracts (green tea, green coffee, chilli pepper) have an antioxidant action, while the caffeine helps improve concentration and increase alertness.

Let's see in detail how the plant extracts contained in Lipoxan New Formula act.

Synephrine, obtained from the immature fruit of Citrus amarantum (bitter orange), is a sympathomimetic amine used for slimming purposes and as a stimulant, stimulant and thermogenic. In fact, this extract favors the mobilization of fats and the reduction of adipose tissue, as well as reducing appetite and stimulating the basal metabolic rate (it causes an increase in caloric expenditure).

Green coffee, obtained from coffee beans that have not yet undergone roasting (roasting), has a high percentage of chlorogenic acid (45%), a vegetable active ingredient with interesting pharmacological activities, and to a lesser extent than normal coffee, caffeine (5%). It is believed that chlorogenic acid can lead to various health benefits, including the modulation of blood sugar, an antioxidant effect and above all the regulation of metabolism, through an inhibition of fat accumulation during adipogenesis.

Green tea, rich in catechins, polyphenols and EGCG, boasts a powerful antioxidant action and the ability to stimulate lipolysis, acting on the fats located in the adipose tissue to promote their oxidation for energy purposes. It also has action on thermogenesis, increasing and stimulating the metabolism.

Anhydrous caffeine is a powerful stimulant that helps improve concentration, endurance and physical performance. It works by increasing energy, elevates body temperature and consequently speeds up the metabolism.

Chili pepper contains capsaicin, an alkaloid with analgesic and soothing action. Even low doses of this natural active ingredient can cause the burning sensation typical of chili peppers: this stress causes a rapid release of adrenaline from the body, making us feel a great energy.

The Lipoxan formula is then completed by the addition of Aframomum melegueta extract (titrated in 6-paradol), commonly known as grains of paradise. This plant, the "Guinea pepper" is known in the phytotherapeutic field for its stimulating and diuretic properties. The empirical use of the grains of this plant has the digestive and intestinal spheres as its main objective, but recent research has highlighted other beneficial properties of these grains, particularly in the context of weight loss. Very interesting clinical studies have in fact confirmed that the intake of grains of paradise can gradually counteract the accumulation of fat, attaching itself to the already existing body fat.

Thanks to these characteristics, Lipoxan New Formula is suitable for those who practice regular physical activity and/or follow a low-calorie diet. Taking this product can help speed up the weight loss process and improve metabolic activity, promoting the reduction of fat tissue.

It is important to underline that the intake of Lipoxan New Formula must always be associated with an active lifestyle and a balanced diet and that the product is suitable for vegetarian and vegan diets.

Scientific references

Harpaz E, Tamir S, Weinstein A, Weinstein Y. The effect of caffeine on energy balance. J Basic Clin Physiol Pharmacol. 2017 Jan 1;28(1):1-10. doi: 10.1515/jbcpp-2016-0090. PMID: 27824614.

Clark KS, Coleman C, Shelton R, Heemstra LA, Novak CM. Caffeine enhances activity thermogenesis and energy expenditure in rats. Clin Exp Pharmacol Physiol. 2019 May;46(5):475-482. doi: 10.1111/1440-1681.13065. Epub 2019 Feb 14. PMID: 30620415; PMCID: PMC6467726.

Bérubé-Parent S, Pelletier C, Doré J, Tremblay A. Effects of encapsulated green tea and Guarana extracts containing a mixture of epigallocatechin-3-gallate and caffeine on 24 h energy expenditure and fat oxidation in men. Br J Nutr. 2005 Sep;94(3):432-6. doi: 10.1079/bjn20051502. PMID: 16176615.

Okla M, Kim J, Koehler K, Chung S. Dietary Factors Promoting Brown and Beige Fat Development and Thermogenesis. Adv Nutr. 2017 May 15;8(3):473-483. doi: 10.3945/an.116.014332. PMID: 28507012; PMCID: PMC5421122.

Tanaka E, Mitani T, Nakashima M, Yonemoto E, Fujii H, Ashida H. Theobromine enhances the conversion of white adipocytes into beige adipocytes in a PPARγ activation-dependent manner. J Nutr Biochem. 2022 Feb;100:108898. doi: 10.1016/j.jnutbio.2021.108898. Epub 2021 Nov 5. PMID: 34748921.

Saito M, Matsushita M, Yoneshiro T, Okamatsu-Ogura Y. Brown Adipose Tissue, Diet-Induced Thermogenesis, and Thermogenic Food Ingredients: From Mice to Men. Front Endocrinol (Lausanne). 2020 Apr 21;11:222. doi: 10.3389/fendo.2020.00222. PMID: 32373072; PMCID: PMC7186310.

Stohs SJ. Safety, Efficacy, and Mechanistic Studies Regarding Citrus aurantium (Bitter Orange) Extract and p-Synephrine. Phytother Res. 2017 Oct;31(10):1463-1474. doi: 10.1002/ptr.5879. Epub 2017 Jul 28. PMID: 28752649; PMCID: PMC5655712.

Net content: 45 g

Warnings: do not exceed the recommended daily dose. Food supplements are not intended as a substitute for a varied diet. A varied and balanced diet and a healthy lifestyle are important. Keep out of the reach of children under three years of age. Do not consume 800 mg or more of epigallocatechin-3-gallate per day. It should not be consumed if other products containing green tea are consumed on the same day. Not to be consumed by pregnant or lactating women and by those under 18 years of age. It should not be consumed on an empty stomach. Keep in a cold and dry place.